Home List of Titles Passive avoidance learning in the young chick results in time- and locus-specific elevations of alpha-tubulin immunoreactivity
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/45578
- Passive avoidance learning in the young chick results in time- and locus-specific elevations of alpha-tubulin immunoreactivity
- Scholey, Andrew B.; Bullock, Sarah; Rose, Steven P. R.
- A monoclonal antibody was used to examine changes in immunoreactivity of the cytoskeletal protein, α-tubulin, following passive avoidance learning in day-old chicks. Postmitochondrial fractions (16,000 g supernatants) were prepared from specific forebrain loci taken at several time points after training and assayed with the anti-α-tubulin antibody, YL1/2. Of the regions examined, elevations in the titre of YL1/2 were found in the left intermediate hyperstriatum ventrale 1 h, 6 h and 24 h following training, in the left lobus parolfactorius 1 h following training and in the right lobus parolfactorius 6 h and 24 h following training. No training-related changes were detected in a third forebrain region, the paleostriatum augmentatum. These results regarding the cellular dynamics of memory formation in the chick confirm and expand on earlier findings from our laboratory.
- Publication type
- Journal article
- Neurochemistry International, Vol. 21, no. 3 (Oct 1992), pp. 343-350
- Publication year
- Alpha tubulin; Animal tissue; Avoidance learning; Brain mitochondrion; Chickens; Enzyme-linked immunosorbent assay; Forebrain; Gallus gallus; Immunoblotting; Immunoreactivity; Learning; Memory; Monoclonal antibodies; Organ specificity; Passive avoidance; Polyacrylamide gel electrophoresis; Prosencephalon; Protein content; Protein localization; Subcellular fractions; Training; Tubulin
- Publisher URL
- Copyright © 1992 Published by Elsevier Ltd.
- Peer reviewed