This study investigates the location criteria (LC) considered when establishing regional treasury centres (RTCs) across three countries Brunei, Singapore and Hong Kong. LC are the important factors that are compulsory for Multinational Companies (MNCs) to examine before setting up RTCs in another region other than where their headquarters are. Comparing Brunei to Asia’s leading international financial centres and locations for RTCs i.e. Singapore and Hong Kong, would assist in identifying whether Brunei is able to host RTCs. The study contributes to the understanding of LC assessment before establishing a RTC in any location. A similar investigation method was conducted, previously applied to European countries, is duplicated and applied to the three Asian countries. The results found that in comparison to Singapore and Hong Kong, Brunei is lacking in terms of the examined LC. Brunei needs to improve these LC to reach the same level of success in Treasury activities as Singapore and Hong Kong.