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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/58198
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- Non-fouling microfluidic chip produced by radio frequency tetraglyme plasma deposition
- Salim, Malinda; Mishra, Gautam; Fowler, Gregory J. S.; O'Sullivan, Brian; Wright, Phillip C.; McArthur, Sally L.
- This Technical Note presents the direct surface modification of a glass/PTFE hybrid microfluidic chip, via radio frequency glow discharge plasma polymerisation of tetraethlylene glycol dimethylether (tetraglyme), to produce hydrophilic, non-fouling, PEO-like surfaces. We use several techniques including X-ray photoelectron spectroscopy (XPS), direct enzyme-linked immunosorbent assays (ELISA) and immunofluorescent imaging to investigate the channel coatings. Our results indicate the successful deposition of a PEO-like coating onto microchannel surfaces that has both solution and shelf stability (>3 months) and is capable of preventing fibrinogen adsorption to the microchannel surfaces.
- Publication type
- Journal article
- Lab on a Chip: Miniaturisation for Chemistry and Biology, Vol. 7, no. 4 (2007), pp. 523-525
- Publication year
- FOR Code(s)
- 03 Chemical Sciences
- Adsorption; ELISA; Enzyme-linked immunosorbent assay; Enzymes; Ether derivative; Ethylene glycol derivative; Fibrinogen; Fluorescence microscopy; Hydrophilicity; Immunofluorescence test; Macrogol; Microfluidics; Molecular stability; Polyethylene glycols; Polymerisation; Radio waves; Radiofrequency; Surface Properties; surface property; Technical notes; X ray emission spectroscopy; X ray photoelectron spectroscopy
- Royal Society of Chemistry
- Publisher URL
- Copyright © 2007 The Royal Society of Chemistry. The authors give the Royal Society of Chemistry the exclusive right and licence throughout the world to edit, adapt, translate, reproduce and publish the Paper in all formats, in all media and by all means (whether now existing or in future devised). Published version of the paper reproduced here for non-commercial purposes only in accordance with the copyright policy of the publisher. This paper is made available for personal use only; no further reuse is permitted.
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