A systematic research into the cladding of stellite 6 on stainless steel by pulsed Nd:YAG laser has been carried out. The effects of pulse energy, pulse frequency, powder mass flow rate and spot overlap on the clad layer height, dilution and heat-affected zone (HAZ) have been examined. It was found that both the clad height and penetration into the substrate increase with the pulse energy, spot overlap and pulse frequency, but the effects of these parameters on dilution are complex. The dilution reaches the lowest value (4%) at the incident energy of 18 and 25 J/pulse, spot overlap of 89% and pulse frequency of 40 Hz. The powder mass flow rate of 22 g/min (for energy of 25 J/pulse and spot overlap of 83%) produces thick clad layer with low dilution but results in the formation of defects. The hardness of the clad layer decreases linearly with increasing dilution. No cracks have been found in single-track clad layers at a spot overlap of 89%, however, cracks occurred at lower spot overlap. These cracks were eliminated by the multi-track cladding when the track increment is less than 1/3 of the width of track, which is believed to be due to the remelting or heat treatment of the previous clad track by the subsequent track. The track bands in multi-track clad show coarser structure, higher element segregation and lower hardness.