Enhanced photothermal therapy assisted with gold nanorods using a radially polarized beam

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/78625

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Title: Enhanced photothermal therapy assisted with gold nanorods using a radially polarized beam
Author(s): Kang, Hong; Jia, Baohua; Li, Jingliang Li; Morrish, Dru; Gu, Min
Abstract: We report on the use of a radially polarized beam for photothermal therapy of cancer cells labeled with gold nanorods. Due to a three-dimensionally distributed electromagnetic field in the focal volume, the radially polarized beam is proven to be a highly efficient laser mode to excite gold nanorods randomly oriented in cancer cells. As a result, the energy fluence for effective cancer cell damage is reduced to one fifth of that required for a linearly polarized beam, which is only 9.3% of the medical safety level.
Publication type: Journal article
Research centre: Swinburne University of Technology. Faculty of Engineering and Industrial Sciences. Centre for Micro-Photonics
Source: Applied Physics Letters, Vol. 96, no. 6 (Feb 2010)
Publication year: 2010
FOR Code(s): 01 Mathematical Sciences; 02 Physical Sciences; 09 Engineering
Keyword(s): Cancer cells; Cellular biophysics; Gold nanorods; Laser beams; Nanoparticle-assisted photothermal therapy
Publisher: American Institute of Physics
ISSN: 0003-6951
Publisher URL: http://dx.doi.org/10.1063/1.3302461
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