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- Shear stress mapping in microfluidic devices by optical tweezers
- Wu, Jing; Day, Daniel; Gu, Min
- We present an optical tweezer sensor for shear stress mapping in microfluidic systems of different internal geometries. The sensor is able to measure the shear stress acting on microspheres of different sizes that model cell based biological operations. Without the need for a spatial modulator or a holographic disk, the sensor allows for direct shear stress detection at arbitrary positions in straight and curved microfluidic devices. Analytical calculations are carried out and compared with the experimental results. It is observed that a decrease in the microsphere size results in an increase in the shear stress the particle experiences.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Engineering and Industrial Sciences. Centre for Micro-Photonics
- Optics Express, Vol. 18, no. 8 (Apr 2010), pp. 7611-7616
- Publication year
- FOR Code(s)
- 0205 Optical Physics; 0903 Biomedical Engineering; 01113 Ophthalmology and Optometry
- Microfluidic systems; Microspheres; Optical tweezers; Shear stress mapping
- Optical Society of America
- Publisher URL
- Copyright © 2010 Optical Society of America. Published version of the paper reproduced here in accordance with the copyright policy of the publisher. This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OE.18.007611. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
- Additional information
- The authors would like to acknowledge Swinburne University of Technology through the Swinburne University Postgraduate Award and the Cooperative Research Centre for Polymer.
- Full text
- Peer reviewed