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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/94556
- Xenotransplantation: a tool for reproductive biology and animal conservation?
- Paris, Monique C. J.; Snow, Melanie; Cox, Shae-Lee; Shaw, Jill M.
- The transplantation of reproductive organs, including ovaries and ovarian tissue, was pioneered over 100 years ago. In the 1960s, ovarian grafting was used as a tool to investigate ovarian function, but with the recent development of more effective cryopreservation protocols for ovarian tissue, germline preservation and propagation have now become realistic goals. This review describes progress in ovarian banking and ovarian tissue transplantation, with emphasis on how fresh and frozen ovarian tissue can be used in assisted reproduction for both humans and animals. This paper focuses most closely on the potential value of xenotransplantation, the transplantation of gonads from one species to another, to conserve rare and endangered species. Specific attention is drawn to the use of xenotransplantation as a strategy for generating viable gametes that can be used to produce live fertile offspring. Other upcoming xenogeneic technologies that may be of potential significance in animal conservation, such as transplantation of whole ovaries or isolated growing follicles, and even male germ cells, are discussed.
- Publication type
- Journal article
- Theriogenology, Vol. 61, no. 2-3 (Jan 2004), pp. 277-291
- Publication year
- FOR Code(s)
- 0702 Animal Production; 0707 Veterinary Sciences
- Animal conservation; Ovarian freezing; Ovarian transplantation; Xenotransplantation
- Publisher URL
- Copyright © 2003 Elsevier Inc. All rights reserved.
- Peer reviewed