Home List of Titles Mesoporous silica particles as templates for preparing enzyme-loaded biocompatible microcapsules
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/150047
- Mesoporous silica particles as templates for preparing enzyme-loaded biocompatible microcapsules
- Yu, A.; Wang, Y.; Barlow, E.; Caruso, F.
- An alternative, facile process for encapsulating biomacromolecules within polyelectrolyte microcapsules using mesoporous silica (MS) spheres as sacrificial templates for both enzyme immobilization and polyelectrolyte multilayer capsule formation, was reported. The encapsulation of of catalase in biocompatible poly(L-lysine) (PLL)/poly(L-glutamic acid) (PGA) was demonstrated. The activity of the catalase in the PLL/PGA microcapsules was examined by measuring the kinetics of hydrogen peroxide (H2O2) decomposition in a stirred system. The method yields microcapsules with high enzyme loading, retained enzyme activity, and enzyme in a free state.
- Publication type
- Journal article
- Advanced Materials, Vol. 17, no. 14 (Jul 2005), pp. 1737-1741
- Publication year
- FOR Code(s)
- 0303 Macromolecular and Materials Chemistry; 0904 Chemical Engineering; 0912 Materials Engineering
- Biocompatibility; Biomaterials; CLSM; Confocal laser scanning microscopy; Drug products; Electrostatics; Encapsulation; Enzymes; Hydrogen peroxide; Macromolecules; Mesoporous silica; Multilayer films; Pesticides; Polyelectrolytes; Silica; Silica-core dissolution; Transmission electron microscopy
- Publisher URL
- Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. The copyright policy of the publisher allows the accepted manuscript of the paper to be reproduced here after a publisher-imposed embargo period.
- Peer reviewed