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Title

Catalytic oxidation of uric acid at the polyglycine chemically modified electrode and its trace determination

Author(s)

Yu, Ai-Min;  Zhang, Hai-Li;  Chen, Hong-Yuan

Abstract

Cyclic voltammetry was undertaken to investigate the electrochemical behavior of uric acid at a polyglycine modified electrode. The modified electrode shows catalytic ability for the oxidation of uric acid, reducing the overpotential by 250 mV in pH 7.0 phosphate buffer solution. The enhanced voltammetric response can be used to determine uric acid. The linear range is between 5.0 x 10(-8) and 4.5 x 10(-6) M with a detection limit as low as 5.0 x 10(-9) M. The relative standard deviation is 1.4% (8 runs) at a concentration of 50 mµM uric acid. The catalytic effect of the modified electrode resulted in the voltammetric resolution of the overlapping of uric acid and ascorbic acid. This allows the simultaneous detection of uric acid and ascorbic acid in the same sample.

Publication type

Journal article

Source

Analyst, Vol. 122, no. 8 (1997), pp. 839-841

Publication year

1997

FOR Code(s)

0301 Analytical Chemistry

Keyword(s)

Amperometric detection;  Carbon-paste electrodes;  Electrocatalytic oxidation;  Polyglycine chemically modified electrode;  Uric acid

Publisher

Royal Society of Chemistry

ISSN

0003-2654

Publisher URL

http://dx.doi.org/10.1039/A607516I

Copyright

Copyright © 1997 The authors. The authors give the Royal Society of Chemistry the exclusive right and licence throughout the world to edit, adapt, translate, reproduce and publish the Paper in all formats, in all media and by all means (whether now existing or in future devised). Published version of the paper reproduced here for non-commercial purposes only in accordance with the copyright policy of the publisher. This paper is made available for personal use only; no further reuse is permitted.

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