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Home List of Titles Fabrication of thionin-toluene diisocyanate modified electrode and its electrocatalytic oxidation to NADH
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/150145
- Fabrication of thionin-toluene diisocyanate modified electrode and its electrocatalytic oxidation to NADH
- Yu, A. M.; Han, J. L.; Yang, K. S.; Zhang, H. L.; Chen, H. Y.
- The chemically modified electrode constructed by chemically cross-linking of redox mediator thionin with toluene diisocyanate(TDI) directly at the surface of a spectrographic graphite electrode shows a significant electrocatalytic activity to the oxidation of reduced nicotinamide adenine dinucleotide (NADH) with oxidation overpotential reduced by 310 mV. In the potential range from -0.1 to 0.3 V, the adsorbed thionin-TDI behaves as a one electron and one proton reversible redox process. The modified electrode achieves a steady-state Current of NADH within 20 s and the detection limit is about 1.5 mu M Furthermore, alcohol dehydrogenase (ADH), NAD(+) were cross-linked directly in aid of the reaction of thionin and TDI on the electrode surface to yield an alcohol reagentless sensor without covering a polymer membrane for protection.
- Publication type
- Journal article
- Chemical Research in Chinese Universities, Vol. 12, no. 3 (Aug 1996), pp. 245-252
- Publication year
- FOR Code(s)
- 03 Chemical Sciences
- Adsorption; Biosensors; Carbon electrodes; Catalytic oxidation; Dihydronicatinamide adenine-dinucleotide; Electrocatalysis; Modified electrodes; Modified graphic electrodes; NADH; TN-TDI derivative
- Jilin Daxue
- Publisher URL
- Copyright © 1996.
- Peer reviewed