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Home List of Titles Antibacterial activity of Acacia Daviesii (M. Bartolome) sp. nov.: a new and rare species identified in North-Eastern Victoria, Australia
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/156641
- Antibacterial activity of Acacia Daviesii (M. Bartolome) sp. nov.: a new and rare species identified in North-Eastern Victoria, Australia
- Kjaerstad, Hilde Lie; McGill, Allison; Palombo, Enzo A.
- The genus Acacia comprises over 1300 species of which nearly 1000 are found in Australia. Numerous species have been used as traditional medicines by the Aboriginal peoples of Australia, although few of the medicinal properties have been investigated, The species Acacia daviesii is a newly discovered plant and is reported to have oily phyllodes which emit a pungent smell. Although there is no documented medicinal use for this particular plant, the traditional use of other Acacia species prompted us to investigate this new species. Aqueous and organic (ethanol, acetone and petroleum ether) extracts of the phyllodes and stems of Acada daviesii were tested for antibacterial activity. With the exception of the aqueous extracts, all were active against the Gram positive bacteria tested (inhibitory concentrations of 200-1600 mg/ ml), while none were active against Gram negative bacteria. Preliminary phytochemical analysis indicated the presence of sugars, steroids, terpenes and flavonoids. Bioautography indicated that common antibacterial fractions were present within the active phyllode and stem extracts. Further investigation of the extracts indicated that they exhibited activity against bacteria implicated in the development of dental caries (Streptococcus mutans and S. sobrinus). Time-kill assays showed that the extracts displayed bactericidal activity within 60 minutes, and they also inhibited glycolytic acid production over a 30 minute time period. In addition, a reduction in biofilm formation was observed at subMIC levels. These finding suggests that extracts, or active compounds within the extracts, may have application in the prevention of oral diseases caused by cariogenic and acidogenic bacteria.
- Publication type
- Book chapter
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences. Environment and Biotechnology Centre
- Utilisation and Management of Medicinal Plants / V. K. Gupta, Auil K. Verma and Sushma Koul (eds.), Chapter 17, pp. 306-318
- Publication year
- Acacia daviesJi; Antibacterial activity; Bioautography; Dental caries; Minimum inhibitory concentration; Phytochemicals
- Daya Publishing House
- 9788170356257, 8170356253
- Publisher URL
- Copyright © 2010.
- Peer reviewed