Nano-rough surfaces produced by glancing angle deposition for protein adsorption measurements and cellular assays - Swinburne Research Bank : Open Access Repository

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Title: Nano-rough surfaces produced by glancing angle deposition for protein adsorption measurements and cellular assays
Author(s): Dolatshahi-Pirouz, A.; Pennisi, C. P. A.; Foss, M.; Chevallier, J.; Zachar, V.; Kingshott, P.; Yoshida, K.; Besenbacher, F.
Abstract: Currently, there is a strong focus on the fabrication of nanostructured artificial surfaces in order to tailor the biological response of artificial materials. The nanostructures are mainly used for more fundamental protein and cell studies, but in some cases also for applications like implants and cell/tissue engineering. Here a simple method to generate nano-rough platinum surfaces with varying morphological characteristics and a well-controlled surface roughness has been employed. The surfaces were fabricated by glancing angle deposition (GLAD) with varying angles and deposition times. Afterwards the biological response of the characterized nanorough samples were examined by protein adsorption and cell adhesion/proliferation assays in order to evaluate their potential as biomaterials surfaces. The effect of the deposition angle,
Publication Type: Conference abstract
Source: Paper presented at the 55th American Vacuum Society (AVS) Annual Symposium and Exhibition, Boston, United States, 19-24 October 2008
Publication Year: 2008
Keyword(s): Artificial materials; Artificial membrane; Artificial surfaces; Cellular assays; Deposition; Fibroblasts; Nano-rough surfaces; Photoelectron spectroscopy; Protein adsorption; Spectroscopy; Substrates; Thin coatings
Publisher: American Vacuum Society
Publisher URL: http://www2.avs.org/symposium2008/Papers/Paper_BI+NC-TuA8.html
Peer Reviewed