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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/202133
- Title
- The effect of d,l-methamphetamine on simulated driving performance
- Author(s)
- Silber, Beata Y.; Croft, Rodney J.; Downey, Luke A.; Camfield, David A.; Papafotiou, Katherine; Swann, Phillip; Stough, Con
- Abstract
- Illicit drugs such as methamphetamine are commonly abused drugs that have also been observed to be prevalent in drivers injured in road accidents. The exact effect of methamphetamine or its specific isomers on driving and driving behaviour have yet to be thoroughly investigated. Twenty healthy recreational illicit stimulant users (ten males, ten females), aged between 21 and 34 years (mean = 24.3 years, SD = 3.4 years), attended two testing sessions involving oral consumption of 0.42 mg/kg d , l- methamphetamine or a matching placebo. The drug administration was counterbalanced, double-blind, and medically supervised. At each session, driving performance was assessed 2.5 h post-drug administration. Mean blood and saliva d , l -methamphetamine concentrations of approximately 90 and 400 ng/ml, respectively, at 2 h and 95 and 475 ng/ml at 3 h were observed. These levels of d , l- methamphetamine were found not to significantly impair, or improve, driving performance at the 2.5-h post-drug administration time point. The findings of this study illustrate that d , l -methamphetamine has no significant effect on simulated driving performance.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences. Centre for Human Psychopharmacology
- Source
- Psychopharmacology, Vol. 219, no. 4 (Feb 2012), pp. 1081-1087
- Publication year
- 2012
- FOR Code(s)
- 1115 Pharmacology and Pharmaceutical Sciences; 1701 Psychology; 1702 Cognitive Science
- Keyword(s)
- Driving; Driving simulators; Illicit drugs; Methamphetamine; Stimulants
- Publisher
- Springer
- ISSN
- 0033-3158
- Publisher URL
- http://dx.doi.org/10.1007/s00213-011-2437-7
- Copyright
- Copyright © Springer-Verlag 2011.
- Peer reviewed
