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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/204194
- Title
- Do bacteria differentiate between degrees of nanoscale surface roughness?
- Author(s)
- Bazaka, Kateryna; Crawford, Russell J.; Ivanova, Elena P.
- Abstract
- Whereas the employment of nanotechnology in electronics and optics engineering is relatively well established, the use of nanostructured materials in medicine and biology is undoubtedly novel. Certain nanoscale surface phenomena are being exploited to promote or prevent the attachment of living cells. However, as yet, it has not been possible to develop methods that completely prevent cells from attaching to solid surfaces, since the mechanisms by which living cells interact with the nanoscale surface characteristics of these substrates are still poorly understood. Recently, novel and advanced surface characterisation techniques have been developed that allow the precise molecular and atomic scale characterisation of both living cells and the solid surfaces to which they attach. Given this additional capability, it may now be possible to define boundaries, or minimum dimensions, at which a surface feature can exert influence over an attaching living organism.This review explores the current research on the interaction of living cells with both native and nanostructured surfaces, and the role that these surface properties play in the different stages of cell attachment.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences
- Source
- Biotechnology Journal, Vol. 6, no. 9 (Sep 2011), pp. 1103-1114
- Publication year
- 2011
- FOR Code(s)
- 1002 Environmental Biotechnology; 1003 Industrial Biotechnology; 1004 Medical Biotechnology
- Keyword(s)
- Bacterial adhesion; Bacterial attachment; Nanoarchitecture; Nanobiotechnology; Nanoroughness
- Publisher
- WILEY-VCH Verlag GmbH & Co. KGaA
- ISSN
- 1860-6768
- Publisher URL
- http://dx.doi.org/10.1002/biot.201100027
- Copyright
- Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
- Additional information
- The authors acknowledge support from the Australian Research Council, the Advanced Manufacturing Co-operative Research Centre, the Australian Institute of Nuclear Science, the Rural Industry Research and Development Corporation and the Department of Agriculture, Fisheries and Forestry of Australia as part of a Science and Innovation Award for Young People in Agriculture, Fisheries and Forestry.
- Peer reviewed
