Home List of Titles In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/210090
- In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy
- Xiong, Jianyu; Li, Yuncang; Hodgson, Peter D.; Wen, Cui'e
- The morphology of nanomaterials significantly affects their physical, chemical, and biological properties. In the present study, nano-hydroxyapatite coatings with different morphologies were produced on the surface of a titanium-niobium shape memory alloy via a hydrothermal process. The effect of the nano-hydroxyapatite coatings on the in vitro proliferation of SaOS-2 osteoblast-like cells was investigated. Factors including crystallinity, surface micro-roughness, and surface energy of the nano-hydroxyapatite coatings were discussed. Results show that in vitro proliferation of the osteoblast-like cells was significantly enhanced on the nano-hydroxyapatite-coated titanium-niobium alloy compared to the titanium niobium alloy without coating. The cell numbers on the nano-hydroxyapatite-coated titanium-niobium alloy changed consistently with the surface energy of the hydroxyapatite coatings. This study suggests that surface energy as a characteristic parameter influencing the in vitro proliferation of osteoblast-like cells was predominant over the crystallinity and surface micro-roughness of the nano-hydroxyapatite coatings.
- Publication type
- Journal article
- Journal of Biomedical Materials Research Part A, Vol. 95A, no. 3 (Dec 2010), pp. 766-773
- Publication year
- FOR Code(s)
- 06 Biological Sciences; 09 Engineering
- Hydrothermal process; In vitro proliferation; Nano-hydroxyapatite coating; Osteoblast-like cells; Titanium-niobium alloy
- John Wiley & Sons
- Publisher URL
- Copyright © 2010 Wiley Periodicals, Inc.
- Peer reviewed