Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine

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Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine

Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/210074

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Title: Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine
Author(s): Li, Yuncang; Li, Meiheng; Hu, Wangyu; Hodgson, Peter; Wen, Cui'e
Abstract: In this study, Mg-xCa (x = 0.5, 1.0, 2.0, 5.0, 10.0, 15.0 and 20.0 %, wt.%, hereafter) and Mg-1Ca-1Y alloys were investigated as new biodegradable bone implant materials. The compressive strength, ultimate strength and hardness of the Mg-Ca alloys increased, whilst the corrosion rate and biocompatibility decreased, with the increase of the Ca content in the Mg-Ca alloys; higher Ca content caused the Mg-Ca alloy to become brittle. Solutions of simulated body fluid (SBF) and modified minimum essential media (MMEM) with the immersion of Mg-xCa and Mg-1Ca-1Y alloys showed strong alkalisation. The yttrium addition to the Mg-Ca alloys does not improve the corrosion resistance of the Mg-1Ca-1Y alloy as expected compared to the Mg-1Ca alloy. It is suggested that Mg-Ca alloys with Ca additions less than 1.0 wt.% exhibited good biocompatibility and low corrosion rate.
Publication type: Journal article
Source: Materials Science Forum: PRICM7: selected papers from the Seventh Pacific Rim International Conference on Advanced Materials and Processing (PRICM7), Cairns, Queensland, Australia, 02-06 August 2010 / Jian-Feng Nie and Allan Morton (eds.), Vol. 654-656, pp. 2192-2195
Publication year: 2010
Keyword(s): Biodegradable materials; Cytotoxicity; Magnesium alloys; Mechanical properties
Publisher: Trans Tech Publications
ISSN: 0255-5476 (series ISSN)
ISBN: 9780878492558, 0878492550
Publisher URL: http://dx.doi.org/10.4028/www.scientific.net/MSF.654-656.2192
Peer reviewed