Graphene oxide nanoparticles as a nonbleaching optical probe for two-photon luminescence imaging and cell therapy

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/217445

Title: Graphene oxide nanoparticles as a nonbleaching optical probe for two-photon luminescence imaging and cell therapy
Author(s): Li, Jing-Liang; Bao, Hong-Chun; Hou, Xue-Liang; Sun, Lu; Wang, Xun-Gai; Gu, Min
Abstract: Herein, it is demonstrated that strong photoluminescence from twophoton excitation can be induced in GO by an ultrafast pulsed laser. The application of this technique to cancer cell imaging, using a gastric cancer cell line (AGS) as an example, is also investigated along with the potential application of the photothermal effects of graphene oxide nanoparticles (GONs) for cancer cell therapy. We observed that intensive microbubbling can be induced by irradiation at a laser power as low as 4 mWin the presence of GONs, which causes instant cell damage.
Publication type: Journal article
Research centre: Swinburne University of Technology. Faculty of Engineering and Industrial Sciences. Centre for Micro-Photonics
Source: Angewandte Chemie - International Edition, Vol. 51, no. 8 (Feb 2012), pp. 1830-1834
Publication year: 2012
FOR Code(s): 03 Chemical Sciences
Keyword(s): Cancer; Graphene oxide; Imaging agents; Photothermal therapy; Two-photon luminescence
Publisher: Wiley VCH Verlag
ISSN: 1433-7851
Publisher URL: http://dx.doi.org/10.1002/anie.201106102
Peer reviewed