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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/219146
- The effect of d-methamphetamine on simulated driving performance
- Silber, Beata Y.; Croft, Rodney J.; Downey, Luke A.; Papafotiou, Katherine; Camfield, David A.; Stough, Con
- Objectives: Methamphetamine is considered to be one of the most popularly abused drugs by drivers; however, its exact effect on driving and driving behaviour has yet to be thoroughly investigated. This being despite methamphetamine's increased prevalence in injured and deceased drivers. Methods: Twenty healthy recreational illicit stimulant users (10 male and 10 female), aged between 21 and 32 years (mean = 25.4 years, SD = 3.3 years) attended two testing sessions involving oral consumption of 0.42 mg/kg d-methamphetamine or a matching placebo. The drug administration was counter-balanced, double-blind, and medically supervised. At each session driving, performance was assessed 2.5 h post drug administration. Results: d-methamphetamine (0.42 mg/kg) did not significantly impair overall simulated driving performance 2.5 h post drug administration. At the individual driving variable level, participants in the d-methamphetamine condition were observed to be driving slower when an emergency situation occurred (T = 44, p < 0.05), but interestingly, participants in both conditions recorded average speeds in excess of the speed limit (100 km/h) when the emergency situations occurred. The d-methamphetamine condition did also produce four times more infringements where participants did not stop at red traffic light in comparison to the placebo, but this effect was only evident at a trend level (T = 7, p = 0.11). Conclusions The findings presented herein suggest that d-methamphetamine administered at the levels supplied did not impair driving performance in a manner consistent with epidemiological evidence. Further research is certainly required to elucidate the effects of various doses of methamphetamine, alone and in combination with other legal and illicit substances.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences. Centre for Human Psychopharmacology
- Human Psychopharmacology: Clinical and Experimental, Vol. 27, no. 2 (Mar 2012), pp. 139-144
- Publication year
- FOR Code(s)
- 1115 Pharmacology and Pharmaceutical Sciences; 1701 Psychology; 1702 Cognitive Sciences
- Driving; Driving performance; Driving simulator; Illicit drugs; Methamphetamines
- John Wiley & Sons
- Publisher URL
- Copyright © 2012 John Wiley & Sons, Ltd.
- Research Projects
- Additional information
- The authors acknowledge support from VicRoads, Melbourne, Australia.
- Peer reviewed