Search Swinburne Research Bank
Home List of Titles Efficient surface modification of biomaterial to prevent biofilm formation and the attachment of microorganisms
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/224622
- Efficient surface modification of biomaterial to prevent biofilm formation and the attachment of microorganisms
- Bazaka, Kateryna; Jacob, Mohan V.; Crawford, Russell J.; Ivanova, Elena P.
- Biomaterials play a fundamental role in disease management and the improvement of health care. In recent years, there has been a significant growth in the diversity, function, and number of biomaterials used worldwide. Yet, attachment of pathogenic microorganisms onto biomaterial surfaces remains a significant challenge that substantially undermines their clinical applicability, limiting the advancement of these systems. The emergence and escalating pervasiveness of antibiotic-resistant bacterial strains makes the management of biomaterial-associated nosocomial infections increasingly difficult. The conventional post-operative treatment of implant-caused infections using systemic antibiotics is often marginally effective, further accelerating the extent of antimicrobial resistance. Methods by which the initial stages of bacterial attachment and biofilm formation can be restricted or prevented are therefore sought. The surface modification of biomaterials has the potential to alleviate pathogenic biofouling, therefore preventing the need for conventional antibiotics to be applied.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences
- Applied Microbiology and Biotechnology, Vol. 95, no. 2 (Jul 2012), pp. 299-311
- Publication year
- Bacterial attachment; Biofilms; Biomaterials; Surface treatment
- Publisher URL
- Copyright © Springer-Verlag 2012.
- Peer reviewed