Stable low-fouling plasma polymer coatings on polydimethylsiloxane

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Title: Stable low-fouling plasma polymer coatings on polydimethylsiloxane
Author(s): Forster, S.; McArthur, S. L.
Abstract: Polydimethylsiloxane (DMS) is a popular material for microfluidics, but it is hydrophobic and is prone to non-specific protein adsorption. In this study, we explore methods for producing stable, protein resistant, tetraglyme plasma polymer coatings on PDMS by combining extended baking processes with multiple plasma polymer coating steps. We demonstrate that by using this approach, it is possible to produce a plasma polymer coatings that resist protein adsorption (< 10 ng/cm(2)) and are stable to storage over at least 100 days. This methodology can translate to any plasma polymer system, enabling the introduction of a wide range of surface functionalities on PDMS surfaces.
Publication type: Journal article
Research centre: Swinburne University of Technology. Faculty of Engineering and Industrial Sciences. Industrial Research Institute Swinburne
Source: Biomicrofluidics, Vol. 6, no. 3 (Sep 2012), article no. 036504
Publication year: 2012
FOR Code(s): 0203 Classical Physics; 0915 Interdisciplinary Engineering; 1007 Nanotechnology
Keyword(s): Adsorption; Biochemistry; Biological techniques; BioMEMS; Coatings; Hydrophobicity; Microfluidics; Molecular biophysics; Plasma materials processing; Polymers; Proteins; Surface treatment
Publisher: American Institute of Physics
ISSN: 1932-1058
Publisher URL: http://dx.doi.org/10.1063/1.4754600
Peer reviewed