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Title

A single beam near-field laser trap for optical stretching, folding and rotation of erythrocytes

Author(s)

Gu, Min;  Kuriakose, Smitha;  Gan, Xiaosong

Abstract

To understand the fundamental mechanical and viscoelastic properties of RBCs, one needs laser tweezers in which cells can not only be trapped, but also be stretched, folded, and rotated. Stretching, folding and rotating an RBC is particularly important in order to reveal the shear elasticity of the RBC membrane. Here we show a single beam near-field laser trapping technique under focused evanescent wave illumination for optical stretching, folding and rotation of a single RBC. This multifunctional manipulation method will provide a new platform for measuring cell properties such as the membrane elasticity, viscoelasticity and deformability.

Publication type

Journal article

Research centre

Swinburne University of Technology. Faculty of Engineering and Industrial Sciences

Source

Optics Express, Vol. 15, no. 3 (2007), p. 1369-1375

Publication year

2007

Keyword(s)

Lasers;  Laser optics;  Laser trapping;  Medical optics;  Biotechnology;  Physical optics;  Total internal reflection

Publisher

Optical Society of America

ISSN

1094-4087

Publisher URL

http://www.opticsinfobase.org/abstract.cfm?id=125724

Copyright

Copyright © 2007 Optical Society of America. Published version of the paper reproduced here in accordance with the copyright policy of the publisher. This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?id=125724. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.

Full text

Peer reviewed