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- Title
- A lymphocyte homing algorithm
- Author(s)
- Brownlee, Jason
- Abstract
- T-lymphocytes are imprinted with chemical information of the general tissue that is exposed to pathogen. T-cells express specific receptors for this chemical signature and preferentially traffic from the recirculation pathway to the infected tissue. This effect is referred to as lymphocyte homing and provides a targeted response to pathogenic invasion. This work proposes a minimal recirculating clonal selection algorithm that is specialised such that lymphocytes preferentially home to tissue locations (nodes in a directed cyclic graph) where they are anticipated to be most useful.
- Publication type
- Technical report
- Research centre
- Swinburne University of Technology. Faculty of Information and Communication Technologies. Centre for Information Technology Research
- Source
- Complex Intelligent Systems : technical reports
- Publication year
- 2007
- Keyword(s)
- AIS; Artificial immune system; Clonal selection; Homing; Migration; Recirculation; T-cell
- Publisher
- Swinburne University of Technology
- Publisher URL
- http://www.ict.swin.edu.au/personal/jbrownlee/#2007
- Copyright
- Copyright © 2007 Jason Brownlee.
- Full text
