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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/39722
- Polymer microstructures for multianalyte protein assay
- Filipponi, Luisa; Ivanova, Elena P.; Wright, Jonathan P.; Pham, Duy K.; Nicolau, Dan V.
- This paper describes the use of a laser-based method to create microstructures within a bilayer system of gold and a non UV-sensitive polymer, poly(methyl methacrylate). Patterned surfaces were achieved through the use of a computer-controlled laser exposure system, comprising a research-grade inverted optical microscope, a pulsed nitrogen laser emitting at 337 nm and a programmable X-Y-Z stage. Those microstructures have proven to be useful for the adsorption of a variety of proteins. The technology has also been applied to an antigen-antibody specific recognition experiment, which proved the feasibility of this system for multianalyte protein assay. In the future, this system will be used as a platform for the optimisation of cell-cell communication within functionalised microstructures. In particular, the functionalisation of these micro-channels with neuropeptides is foreseen, with the aim of investigating effects that influence nerve regeneration.
- Publication type
- Conference paper
- Research centre
- Swinburne University of Technology. Industrial Research Institute Swinburne
- Profiles in Industrial Research: Knowledge and Innovation 2002, St Kilda, Victoria, Australia, 15-19 July 2002, pp. 308-312
- Publication year
- Nerve regeneration; Polymer microstructures; Protein adsorption
- Industrial Research Institute Swinburne, Swinburne University of Technology
- Publisher URL