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Home List of Titles Ultra-low energy threshold for cancer photothermal therapy using transferrin-conjugated gold nanorods
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/40424
- Ultra-low energy threshold for cancer photothermal therapy using transferrin-conjugated gold nanorods
- Li, Jing-Liang; Gu, Min; Day, Daniel J.
- Gold nanoparticles have shown potential applications for cancer detection and localized photothermal therapy (PTT). Among the gold nanoparticles that have been studied, gold nanorods are of particular interest because of their tuneable near-infrared (NIR) absorption and the recent success in their size-controlled, large-scale synthesis. The strong two-photon photoluminescence (TPL) of gold nanorods render them good contrast agents for cancer cell imaging under two-photon excitation, which makes it more suitable to three-dimensional nonlinear optical imaging of biological samples. Despite the successful application of gold nanorods in PTT and in vitro cancer imaging, this technique still has a long way to go before it can be implemented clinically. [Introduction]
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Engineering and Industrial Sciences. Centre for Micro-Photonics
- Advanced Materials, Vol. 20, no. 20, pp. 3866-3871
- Publication year
- Cancer; Cancer cells; Gold nanorods; Near-infrared; NIR; Photothermal therapy; Polarisation; PTT; Targeting; Therapy; TPL; Transferring; Two-photon photoluminescence
- Publisher URL
- Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
- Additional information
- The authors would like to thank Mr Peter Zijlstra for help with the TEM measurements and the Australia Research Council for financial support.
- Peer reviewed