Active control of silver nanoparticles spacing using dielectrophoresis for surface-enhanced Raman scattering

Author(s)

Chrimes, Adam F.; Khoshmanesh, Khashayar; Stoddart, Paul R.; Kayani, Aminuddin A.; Mitchell, Arnan; Daima, Hemant; Bansal, Vipul; Kalantar-zadeh, Kourosh

Abstract

We demonstrate an active microfluidic platform that integrates dielectrophoresis for the control of silver nanoparticles spacing, as they flow in a liquid channel. By careful control of the nanoparticles spacing, we can effectively increase the surface-enhanced Raman scattering (SERS) signal intensity based on augmenting the number of SERS-active hot-spots, while avoiding irreversible aggregation of the particles. The system is benchmarked using dipicolinate (2,6-pyridinedicarboxylic acid) (DPA), which is a biomarker of Bacillus anthracis. The validity of the results is discussed using several complementing characterization scenarios.

Publication year

2012

Publication type

Journal article

Source

Analytical Chemistry, Vol. 84, no. 9 (May 2012), pp. 4029-4035

ISSN

0003-2700

Publisher

American Chemical Society

Copyright

Copyright © 2012 American Chemical Society.

Details